The Incidence and Risk Factors for Hospital-acquired MRSA Carriage in Rajavithi Hospital
Tavatchai jariyasethpong M.D., Nalinwan Wongsawat M.D.
Abstract
Background: Colonization of
methicillin-resistant Staphylococcus aureus (MRSA), an important
nosocomial pathogen, has been described as a risk factor for subsequent MRSA
infection. This study was assigned to
find the incidence and risk factors for hospital-acquired MRSA colonization which
was done in general medicine wards of Rajavithi Hospital.
Methods: Patients admitted to 4 general
medicine wards were evaluated. Anterior
nares samples were obtained for culture within 48 hours of admission, at 3
days, and weekly after hospitalization. The probable risk factors for nasal carriage were recorded for
assessment.
Results: HA-MRSA and CA-MRSA
were found in 59 (16%) of 364 patients and 25 (7%) of 364 patients
subsequently. Independent factors
associated with an increased risk of MRSA colonization included history of MRSA
infection before this admission (RR, 6.84; 95%CI, 1.27-37.01) and duration of
admission (RR, 1.08; 95%CI, 1.05-1.11). Twenty-five points four percent of HA-MRSA colonized patients were
subsequently developed MRSA infection.
Conclusions: The high incidence of MRSA nasal carriage in the
general medicine wards is a high burden. Admitted to this wards for one day increases the risk of MRSA
colonization. Infection control measures
need to be focus to all patients who admitted to this wards. This hospital needs a better policy for
infection control and prevention. (J
Infect Dis Antimicrob Agents 2015;32:119-33.)
Keyword : MRSA carriage, MRSA colonization, nosocomial MRSA, hospital-acquired MRSA
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